The Twisted Tale of Amanda Knox dramatises the former student’s wrongful conviction for the murder of her flatmate Meredith Kercher. The new TV series, commissioned by Hulu, will air on Disney+ in 2025.

The true story of Meredith’s murder in 2007, and the subsequent police investigation, remains one of the most controversial crimes in living memory.

And now, Amanda’s 16-year “fight for freedom” is being dramatised in a TV series, with actress Grace Van Patten playing the titular role.

The series had the working title of Amanda, but is now called The Twisted Tale of Amanda Knox. Here’s everything you need to know about the TV drama, based on the shocking true story.

Grace Van Patten as Amanda Knox in the new drama [Credit: Disney+]

What is The Twisted Tale of Amanda Knox about?

Hulu has commissioned a TV drama entitled The Twisted Tale of Amanda Knox, which will air on Disney+. It is based on the disturbing true story of murdered Meredith Kercher, and Amanda Knox, the flatmate who was wrongfully convicted of killing her.

Amanda and Meredith were both exchange students sharing an apartment in Perugia, Italy. In 2007, a 20-year-old Amanda returned home after spending the night with her boyfriend Raffaele Sollecito. She called police when she discovered Meredith’s bedroom door locked and blood in the bathroom. Tragically, Meredith was found dead. She had been murdered in her own home.

After the investigation, police arrested Amanda Knox for the murder. In 2009, a jury convicted her of murdering her roommate, Meredith Kercher. Amanda subsequently spent four years in jail fighting to prove her innocence.

She was eventually acquitted in 2011, and released from jail. The Hulu/Disney+ drama will tell Amanda’s story.

The synopsis reads: “Centres on Amanda Knox’s harrowing journey after being wrongfully imprisoned for her roommate’s murder, her battle to prove her innocence and regain her freedom.”

How can I watch Amanda Knox drama? When’s the start date?

The Twisted Tale of Amanda Knox will air on Hulu (a US-based streaming service), and Disney+.

The Amanda Knox drama will be available to those with a Disney+ subscription in the UK.

It will stream from Wednesday, August 20, 2025.

Sharon Horgan portrays Amanda Knox’s mother [Credit: Disney+]

How many episodes is it?

The Twisted Tale of Amanda Knox is an eight-episode limited series.

Each episode is expected to be around an hour long. Disney+ primarily releases new episodes of its series on a weekly schedule, with one episode being released at a time.

Who is in the cast of The Twisted Tale of Amanda Knox?

Actress Grace Van Patten stars as Amanda Knox in the upcoming Disney+ drama. New York-born Grace is known for playing Lucy Albright in Tell Me Lies, and Zoe Marconi in Nine Perfect Strangers.

Andie MacDowell’s daughter Margaret Qualley – star of The Substance – was originally cast in the role of Amanda Knox. However, she left the project due to scheduling conflicts.

Irish actress Sharon Horgan will play Edda Mellas, Amanda’s mum. Sharon’s known for writing and starring in Catastrophe, Bad Sisters, and Pulling.

Giuseppe De Domenico will portray Amanda’s Italian boyfriend Raffaele Sollecito. The Sicily-born actor is known for #Goldfish, and ZeroZeroZero.

Meanwhile, Rome-born actor Francesco Acquaroli plays Italian magistrate Giuliano Mignini.

Dopesick’s John Hoogenakker also stars in an undisclosed role, and Roberta Mattei plays Monica Napoleoni, the head of the homicide division in Perugia.

Amanda Knox’s trial provoked a media storm at the time [Credit: Hulu/Disney+]

Where is Amanda Knox now?

American Amanda Knox is currently 37, and an author, activist, and journalist. She is married, with two kids.

Her memoir, Waiting to be Heard, became a best seller in 2013. She has subsequently written the book, Free: My Search for Meaning.

In 2018, she began hosting The Scarlet Letter Reports, a television series examining the “gendered nature of public shaming”.

Amanda acts as executive producers on the new drama, alongside Monica Lewinsky, Warren Littlefield, Lisa Harrison, Ann Johnson, and Graham Littlefield.

What is the true story behind the Meredith Kercher murder?

Meredith Kercher was murdered on November 01, 2007. The British student, who was on exchange from the University of Leeds, was just 21 when she was killed in her Perugia apartment in Italy.

She was found dead on the floor of her room. Her body was discovered in her bedroom, partly undressed with multiple stab wounds. She had also been sexually assaulted.

In 2009, American suspect Amanda Knox and her Italian former boyfriend, Raffaele Sollecito, were convicted of Meredith’s murder. A judge sentenced them to 26 and 25 years in prison respectively.

Knox and Sollecito spent four years in prison after initially being convicted of Kerchers murder.

They were acquitted in 2011 before being convicted again in 2014 by an appeals court in Florence, which ruled that the multiple injuries inflicted on Kercher’s body proved that Rudy Guede could not have acted alone.

However, Italy’s highest court overturned the decision in a definitive ruling in 2015. It detailed the “stunning flaws” in the investigation that led to the convictions of Knox and Sollecito.

Grace Van Patten and Giuseppe De Domenico as Amanda Knox and Raffaele Sollecito [Credit: Disney+]

Who killed Meredith Kercher?

Rudy Guede was later convicted of the murder of the British student Meredith Kercher.

A known burglar, Rudy’s bloody fingerprints were found on Meredith’s possessions. He was convicted of murder in a fast-track trial and was sentenced to 30 years imprisonment, later reduced to 16 years. He is now free.

In December 2020, an Italian court ruled that Guede could complete his term by doing community service. He was freed from prison after completing 13 years of a 16-year sentence.

Rudy Guede always denied murdering Meredith Kercher, even though his DNA was found on her body and in her bedroom.

Why was the Meredith Kercher murder so controversial?

Meredith Kercher’s tragic murder, and the subsequently wrongful conviction of Amanda Knox and her boyfriend was THE news story at the time. Amanda Knox’s face was on the front cover of every newspaper and magazine.

In what has been described as a trial by media, Amanda and her boyfriend’s actions and reactions were scrutinised – and found by many to be suspicious. Amanda did not display the required level of sadness at the death of her flatmate.

Totally overshadowing Meredith’s murder, Amanda Knox was described as Foxy Knoxy by some press. She was labelled a party girl, and called a “she-devil” by prosecutors.

Knox’s “inappropriate” behaviour after the murder was noted by police officers and others in the murder trial. A senior police officer told the court in Perugia that both Knox and Sollecito had a “strange attitude” when they were brought to the police station for questioning.

Amanda Knox was seen turning cartwheels in the police station, the court heard. On one occasion, Knox sat on Sollecito’s lap while they were questioned.

Amanda continues to be criticised to this day. She is now being accused of “profiting from murder” with the new TV series about her. The family of the murdered Meredith Kercher say it is “difficult to understand” how the show “serves any purpose”.

Amanda Knox has been the subject of multiple TV and film projects, including a 2011 Lifetime movie, and a 2016 Netflix documentary.

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The start date of The Twisted Tale of Amanda Knox is Wednesday, August 20, 2025 on Disney+.